For Pharmacy

Vial Cost
Acquisition cost should be evaluated alongside dosing, redosing, and overall utilization.
Dose (mg/kg)
Per-kilogram dosing affects total volume, preparation, and drug usage.
Redose Rate
Redosing frequency can influence total cost, workflow, and patient exposure.
Onset of Action
Speed of FiO₂ reduction may impact respiratory management decisions.
Volume & Viscosity
Formulation characteristics affect delivery efficiency and ease of administration.
Administration Time
Delivery time impacts nursing and respiratory therapy workflow.
Administration Complications
Rates of delivery-related complications inform safety assessments.
Reflux
Reflux may reduce effective dose delivery and clinical response.
Adverse Events
Overall safety profile supports formulary and protocol decisions.
MV & Oxygen Duration
Impact on ventilation and oxygen days may affect resource utilization.
Less Invasive Ventilation Compatibility
Compatibility with less invasive approaches supports evolving NICU practices.
Pharmacoeconomics
Total cost of care extends beyond acquisition price alone.
Protocol Alignment
Surfactant choice should support institutional care pathways.
Administration & Storage
Storage, handling, and preparation affect pharmacy operations.
Clinical Evidence
Depth and quality of evidence support informed selection.
