For premature infants with Respiratory Distress Syndrome (RDS), deliver the same dose of Infasurf (105mg/kg), in half the volume with Infasurf DS (1.5ml/kg) .

Easier on patients and providers alike.

Infasurf DS - Designed for the way newborns are cared for today - supporting gentler, less invasive surfactant delivery in the modern neonatal practice.

Faster and Easier Administration

The lower volume required for administration made Infasurf DS easier to give than Infasurf. Using only one aliquot instead of two, resulted in less surfactant reflux, less need for positive pressure breaths to clear refluxed surfactant, and overall shorter administration times.

Complications, interventions, and duration of surfactant administration. N=6 for each study group. Mean + Standard Error.

Y-axis unit is percent for reflux, number for positive pressure breaths and seconds for duration.

Asterisk indicates statistically different by unpaired t-test, p<0.05.

Infasurf DS treats up to a 1200 gram baby.

Same dose, half the volume.

Infasurf DS performed as well as Infasurf in regard to improved ventilation after administration

VEIs over the entire course of study for the two surfactant groups. N=6 for each study group. Mean + Standard Error.

VEI in both surfactant groups increased significantly over time by repeated measures ANOVA, p<0.05. Changes in VEI over time were not statistically different between surfactant groups.

Infasurf DS performed as well as Infasurf in regard to improved ventilation after administration

a/A over the entire course of study for the two surfactant groups. N=6 for each study group. Mean + Standard Error.
a/A in both surfactant groups increased significantly over time by repeated measures ANOVA, p<0.05. Changes in a/A over time were not statistically different between surfactant groups.

Representative lamb chest radiographs at pre-intervention (T=0) and 15 minutes after intervention (T=15)